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Browsing by Author "Artemyev, N. O."

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A conformational switch in the inhibitory gamma-subunit of PDE6 upon enzyme activation by transducin

Granovsky, A. E.; Artemyev, N. O. (2001)
Assays of G Protein/cGMP-Phosphodiesterase Interactions

Granovsky, A. E.; Artemyev, N. O. (2002)
Direct interaction of the inhibitory gamma-subunit of Rod cGMP phosphodiesterase (PDE6) with the PDE6 GAFa domains

Muradov, K. G.; Granovsky, A. E.; Schey, K. L.; Artemyev, N. O. (2002)
Identification of Effector Residues on Photoreceptor G Protein, Transducin

Natochin, М.; Granovsky, А. Е.; Artemyev, N. O. (1998)

Transducin is a photoreceptor-specific heterotrimeric GTP-binding protein that plays a key role in the vertebrate visual transduction cascade. Here, using scanning site-directed mutagenesis of the chimeric G at/Gai1a-sub ...
Identification of the y Subunit-interacting Residueson Photoreceptor cGMP Phosphodiesterase, PDE6 a

Granovsky, A. E.; Artemyev, N. O. (200)
Inhibition of Photoreceptor cGMP Phosphodiesterase by Its y Subunit

Granovsky, A. E.; Muradov, K. G.; Artemyev, N. O. (2000)
Mutation in rod PDE6 linked to congenital stationary night blindness impairs the enzyme inhibition by its gamma-subuni

Muradov, K. G.; Granovsky, A. E.; Artemyev, N. O. (2003)
Partial Reconstitution of Photoreceptor cGMP Phosphodiesterase Characteristics in cGMP Phosphodiesterase-5

Granovsky, A. E.; Artemyev, N. O. (2001)
Potency and mechanism of action of E4021, a type 5 phosphodiesterase isozyme-selective inhibitor, on the photoreceptor phosphodiesterase depend on the state of activation of the enzyme

D'Amours, M. R.; Granovsky, A. E.; Artemyev, N. O.; Cote, R. H. (1999)
Probing Domain Functions of Chimeric PDE6a/PDE5 cGMP-Phosphodiesterase

Granovsky, A. E.; Natochin, M.; McEntaffer, R. L.; Haik, T. L.; Francis, S. H.; Corbin, J. D.; Artemyev, N. O. (1998)
Probing functional interfaces of rod PDE gamma-subunit using scanning fluorescent labeling

Granovsky, A. E.; McEntaffer, R.; Artemyev, N. O. (1998)
Regulation of Transducin GTPase Activity by Human Retinal RGS

Natochin, M.; Granovsky, A. E.; Artemyev, N. O. (1997)
Roles of the Transducin a-Subunita4-Helix/ a4- b6Loopinthe Receptor and Effector Interactions

Natochin, M.; Granovsky, A. E.; Muradov, K. G.; Artemyev, N. O. (1999)

The visual GTP-binding protein, transducin, couples light-activated rhodopsin (R*) with the effector enzyme, cGMP phosphodiesterase in vertebrate photoreceptor cells. The region corresponding to the a4-helix and a4-b6 ...
The y Subunit of Rod cGMP-Phosphodiesterase Blocks the Enzyme Catalytic Site

Granovsky, A. E.; Natochin, M.; Artemyev, N. O. (1997)

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